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In these studies, one 15-min infusion of 5 mg of zoledronic acid was compared to 60 days of oral risedronate (Actonel) (30 mg per day) in a total of 347 patients with Paget disease of the bone.

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If history or physical exam suggests dehydration, treatment should not be given until the patient is normovolemic.

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The 6 percent of women who had five or more risk factors and calcaneal bone density in the lowest third for their age had an incidence of hip fracture of 27 (95 percent confidence interval, 20 to 34) per 1000 woman-years and had 62 (32 percent) of the hip fractures reported.

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It was a horrible drug for me and I will tell everyone “It Is A Horrible Drug for anyone other than Bone Cancer Patients.

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