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Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension.

In the 9-year post-DCCT follow-up of the EDIC cohort, participants previously randomized to the intensive arm had a significant 57% reduction in the risk of nonfatal myocardial infarction (MI), stroke, or CVD death compared with those previously in the standard arm ().

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The concomitant use of olmesartan medoxomil and hydrochlorothiazide was evaluated for safety in 1243 hypertensive patients.

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Treating hypertensive patients with a history of stroke for 8 consecutive weeks with olmesartan decreased BP, and increased or preserved the blood flow and CRC in both the affected and unaffected sides of the brain.

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Effects of ACE Inhibitors on Long-Term Outcome of Renal Transplant Recipients.

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MI, stroke, death) in patients with diabetes (), thus further supporting the use of these agents in patients with microalbuminuria, a CVD risk factor.

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It is recommended as adjunctive therapy in the first year after an acute coronary syndrome or as alternative therapy in aspirin-intolerant patients.

Despite better microvascular outcomes, intensive insulin therapy was associated with a high rate of severe hypoglycemia (62 episodes per 100 patient-years of therapy).

Management: When amifostine is used at chemotherapy doses, blood pressure lowering medications should be withheld for 24 hours prior to amifostine administration.

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Thus, cautions are warranted when interpreting the present results into other populations including more severely hypertensive or more symptomatic CHF patients.

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DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes.

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In addition, we discuss recent studies suggesting a role for hyperuricemia and hypokalemia in mediating metabolic abnormalities and renal disease induced by thiazides.

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Chrysant SG, Marbury TC, Silfani TN Use of 24-h ambulatory blood pressure monitoring to assess blood pressure control: a comparison of olmesartan medoxomil and amlodipine besylate.

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